> Sittewelle, M. & Royle, S.J. (2023) Passive diffusion accounts for the majority of intracellular nanovesicle transport. Life Sci Alliance. 7 (1) e202302406. doi: 10.26508/lsa.202302406 | Link
	> Küey, C., Sittewelle, M., Larocque, G., Hernández-González, M. & Royle, S.J. (2022) Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation. eLife 78929. doi: 10.7554/eLife.78929 | Link
	> Ferrandiz, N., Downie, L., Starling, G.P. & Royle, S.J. (2022) Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes. J Cell Biol. 221: jcb.202203021. doi: 10.1083/jcb.202203021 | Link | Spotlight | Year in Cell Biology
	> Smith, S.M., Larocque, G., Wood, K.M., Morris, K.L., Roseman, A.M., Sessions, R.B., Royle, S.J. & Smith, C.J. (2021) Multi-modal adaptor-clathrin contacts drive coated vesicle assembly. EMBO J. e108795. doi: 10.15252/embj.2021108795 | Link
	> Larocque, G., Moore, D.J., Sittewelle, M., Kuey, C., Hetmanski, J.H.R, La-Borde, P.J., Wilson, B.J., Clarke, N.I., Caswell, P.T. & Royle, S.J. (2021) Intracellular nanovesicles mediate α5β1 integrin trafficking during cell migration. J. Cell Biol. 220: e202009028. doi: 10.1083/jcb.202009028 | Link
	> Ryan*, E.L., Shelford*, J., Massam-Wu, T., Bayliss, R. & Royle, S.J. (2020) Defining endogenous TACC3-chTOG-clathrin-GTSE1 interactions at the mitotic spindle using induced relocalization. J. Cell Sci. 134(3):jcs255794. doi: 10.1242/jcs.255794 | Link
	> Larocque, G., La-Borde, P.J., Clarke, N.I., Carter, N.J. & Royle, S.J. (2020) Tumor Protein D54 defines a new class of intracellular transport vesicles. J. Cell Biol. 219: e201812044. doi: 10.1083/jcb.201812044. | Link
	> Küey, C., Larocque, G., Clarke, N.I & Royle, S.J. (2019) Unintended inhibition of protein function using GFP nanobodies in human cells. J. Cell Sci. 132: jcs234955. doi: 10.1242/jcs.234955. | Link
	> Clarke, N.I. & Royle, S.J. (2018) FerriTag is a new genetically-encoded inducible tag for correlative light-electron microscopy. Nat. Commun., 9: 2604. doi: 10.1038/s41467-018-04993-0. | Link
	> Burgess, S.G., Mukherjee, M., Sabir, S., Joseph, N., Gutierrez-Caballero, C., Richards, M.W., Huguenin-Dezot, N., Chin, J.W., Kennedy, E.J., Pfuhl, M., Royle, S.J., Gergely, F. & Bayliss, R. (2018) Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic alpha-helix. EMBO J, 37, e97902. doi: 10.15252/embj.201797902. | Link
	> Wood, L.A., Larocque, G., Clarke, N.I., Sarkar, S. & Royle, S.J. (2017) New tools for “hot-wiring” clathrin-mediated endocytosis with temporal and spatial precision J. Cell Biol., 216: 4351-65. doi: 10.1083/jcb.201702188. | Link
	> Sarkar, S., Ryan, E.L. & Royle, S.J. (2017) FGFR3–TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindle Open Biol., 7: 170080. doi: 10.1098/rsob.170080. | Link
	> Nixon*, F.M., Honnor*, T.R., Clarke, N.I., Starling, G.P., Beckett, A.J., Johansen, A.M., Brettschneider, J.A., Prior, I.A. & Royle, S.J. (2017) Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis J. Cell Sci., 130: 1845-55. doi: 10.1242/jcs.203877. | Link
	> Auckland, P., Clarke, N.I., Royle, S.J. & McAinsh, A.D. (2017) Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment J. Cell Biol., 216: 1623-39. doi: 10.1083/jcb.201607096. | Link
	> Nixon, F.M., Gutiérrez-Caballero, C., Hood, F.E., Booth, D.G., Prior, I.A. & Royle, S.J. (2015) The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle eLife, 4: e07635. doi: 10.7554/eLife.07635. | Link | On the cover
	> Gutiérrez-Caballero, C., Burgess, S.G., Bayliss, R. & Royle, S.J. (2015) TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation Biol. Open, 4: 170-9. doi: 10.1242/bio.201410843. | Link | On the cover
	> López-Murcia, F.J., Royle**, S.J. & Llobet**, A. (2014) Presynaptic clathrin levels are a limiting factor for synaptic transmission J. Neurosci., 34: 8618-8629. | Link | On the cover
	> Willox, A.K., Sahraoui, Y.M.E. & Royle, S.J. (2014) Non-specificity of Pitstop 2 in clathrin-mediated endocytosis Biol. Open, 3: 326-31. doi: 10.1242/bio.20147955. | Link
	> Kaur, S., Fielding, A.B., Gassner, G., Carter, N.J. & Royle, S.J. (2014) An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis eLife 3: e00829 | Link | PDF
	> Hood, F.E., Williams, S.J., Burgess, S.G., Richards, M.W., Roth, D., Straube, A., Pfuhl, M., Bayliss**, R. & Royle**, S.J. (2013) Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding. J. Cell Biol. 202: 463-78. | Link | PDF
	> Cheeseman, L.P., Harry, E.F., McAinsh, A.D., Prior, I.A., Royle, S.J. (2013) Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension. J. Cell Sci. 126: 2102-13. | Link | PDF | SI
	> Willox, A.K. & Royle, S.J. (2012) Stonin 2 is a major adaptor protein for clathrin-mediated synaptic vesicle retrieval. Curr. Biol., 22: 1435-9. | Link | PDF | On the cover
	> Fielding, A.B., Willox, A.K., Okeke, E. & Royle, S.J. (2012) Clathrin-mediated endocytosis is inhibited during mitosis. Proc. Natl. Acad. Sci. U. S. A., 109: 6572-7. | Link | PDF | On the cover
	> Willox, A.K. & Royle, S.J. (2012) Functional analysis of interaction sites on the N-terminal domain of clathrin heavy chain. Traffic, 13: 70-81. | Link | PDF
	> Blixt, M.K.E. & Royle, S.J. (2011) Clathrin heavy chain gene fusions expressed in human cancers: analysis of their cellular functions. Traffic, 12: 754-61. | Link | PDF
	> Cheeseman, L.P., Booth, D.G., Hood, F.E., Prior, I.A. & Royle, S.J. (2011) Aurora A kinase activity is required for localisation of TACC3/ch-TOG/clathrin inter-microtubule bridges. Commun. Integr. Biol., 4: 409-12. | Link | OA | PDF
	> Booth*, D.G., Hood*, F.E., Prior, I.A. & Royle, S.J. (2011) A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO J., 30: 906-19. | Link | PDF | SI | Rev
	> Granseth, B., Odermatt, B, Royle, S.J. & Lagnado, L. (2009) Comment on "The Dynamic Control of Kiss-and-Run and Vesicular Reuse Probed with Single Nanoparticles". Science, 325: 1499. | Link | PDF
	> Hood, F.E. & Royle, S.J. (2009) Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis. J. Cell Sci., 122: 2185-90. | Link | PDF | SI
	> Granseth*, B., Odermatt*, B., Royle, S.J. & Lagnado, L. (2006) Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron, 51(6): 773-86. | Link | PDF | SI | Movie
	> Royle, S.J. & Lagnado, L. (2006) Trimerisation is important for the function of clathrin at the mitotic spindle. J. Cell Sci., 119 (Pt 19): 4071-8. | Link | PDF | SI
	> Royle, S.J., Bright, N.A. Lagnado, L. (2005) Clathrin is essential for the function of the mitotic spindle. Nature, 434: 1152-7. | Link | PDF | SI
	> Royle, S.J., Qureshi, O.S., Bobanovic, L.K., Evans, P.R., Owen, D.J. & Murrell-Lagnado, R.D. (2005) Non-canonical YXXGPhi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors. J. Cell Sci., 118 (Pt 14): 3073-80. | Link | PDF | SI
	> Royle, S.J., Bobanovic, L.K. & Murrell-Lagnado, R.D. (2002) Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor. J. Biol Chem., 277: 35378-85. | Link | PDF | SI
	> Bobanovic, L.K., Royle, S.J. & Murrell-Lagnado, R.D. (2002) P2X receptor trafficking in neurons is subunit specific. J. Neurosci., 22: 4814-24. | Link | PDF
	> Royle, S.J., Collins, F.C., Rupniak, H.T., Barnes, J.C. & Anderson, R. (1999) Behavioural analysis and susceptibility to CNS injury of four inbred strains of mice. Brain Res., 816: 337-49. | Pubmed | PDF

Collaborative papers

	> Nahorski, M.S., Al-Gazali, L., Hertecant, J., Owen, D.J., Borner, G.H.H., Chen, Y., Benn, C.L., Carvalho, O.P., Shaikh, S.S., Phelan, A., Robinson, M.S., Royle, S.J. & Woods, C.G. (2015) A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development. Brain, 138: 2147-60. doi: 10.1093/brain/awv149. | Link
	> O'Regan, L., Sampson, J., Richards, M.W., Knebel, A., Roth, D., Hood, F.E., Straube, A., Royle, S.J., Bayliss, R. & Fry, A.M. (2015) Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression. J. Cell Biol., 209: 349-358. | Link
	> Qureshi, O.S., Kaur, S., Hou, T., Jeffery, L.E., Poulter, N.S., Briggs, Z., Kenefeck, R., Willox, A.K., Royle, S.J., Rappoport, J.Z. & Sansom, D.M. (2012) Constitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation. J. Biol. Chem., 287: 9429-40. | Link | PMC

* = equal contribution
** = joint corresponding authors

Preprints

Coming soon...

Preprint only

> Martins Ratamero, E. & Royle, S.J. (2019) Calculating the maximum capacity of intracellular transport vesicles bioRxiv, doi: 10.1101/555813. | Link 20 Feb 2019

Now published

> Sittewelle, M. & Royle, S.J. (2023) Passive diffusion accounts for the majority of intracellular vesicle transport bioRxiv, doi: https://doi.org/10.1101/2023.05.10.540182. | Link 11 May 2023
> Küey, C., Sittewelle, M., Larocque, G., Hernández-González, M. & Royle, S.J. (2022) Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation bioRxiv, doi: https://doi.org/10.1101/2022.03.21.485220. | Link 21 Mar 2022 | Published in eLife 20 Jul 2022
> Ferrandiz, N., Downie, L., Starling, G.P. & Royle, S.J. (2021) Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes bioRxiv, doi: https://doi.org/10.1101/2021.04.23.441091. | Link 23 Apr 2021 | Published in J Cell Biol 6 Jun 2022
> Smith, S.M., Larocque, G., Wood, K.M., Morris, K.L., Roseman, A.M., Sessions, R.B., Royle, S.J. & Smith, C.J. (2021) Multi-modal adaptor-clathrin contacts drive coated vesicle assembly bioRxiv, doi: https://doi.org/10.1101/2021.05.22.445240. | Link 22 May 2021 | Published in EMBO J 6 Sep 2021
> Larocque, G., La-Borde, P.J., Wilson, B.J., Clarke, N.I., Moore, D.J., Caswell, P.T. & Royle, S.J. (2020) Intracellular nanovesicles mediate integrin trafficking during cell migration bioRxiv, doi: https://doi.org/10.1101/2020.08.19.257287. | Link 19 Aug 2020 | Published in J Cell Biol 22 July 2021
> Ryan, E.L., Shelford, J., Massam-Wu, T., Bayliss, R. & Royle, S.J. (2020) Defining endogenous TACC3–chTOG–clathrin–GTSE1 interactions at the mitotic spindle using induced relocalization bioRxiv, doi: https://doi.org/10.1101/2020.07.01.181818. | Link 01 Jul 2020 | Published in J Cell Sci 30 Dec 2020
> Kuey, C., Larocque, G., Clarke, N.I & Royle, S.J. (2019) Unintended inhibition of protein function using GFP nanobodies in human cells bioRxiv, doi: 10.1101/590984. | Link 27 Mar 2019 | Published in J Cell Sci 10 Oct 2019
> Larocque, G., La-Borde, P.J., Clarke, N.I., Carter, N.J. & Royle, S.J. (2019) Tumor Protein D54 defines a new class of intracellular transport vesicle bioRxiv, doi: 10.1101/481754. | Link 28 Nov 2018 | Published in J Cell Biol 31 Oct 2019
> Clarke, N.I. & Royle, S.J. (2016) FerriTag: A Genetically-Encoded Inducible Tag for Correlative Light-Electron Microscopy bioRxiv, doi: 10.1101/095208. | Link 18 Dec 2016 | Published in Nat Commun 04 July 2018
> Nixon*, F.M., Honnor*, T.R., Starling, G.P., Beckett, A.J., Johansen, A.M., Brettschneider, J.A., Prior, I.A. & Royle, S.J. (2016) Microtubule organization within mitotic spindles revealed by serial block face scanning EM and image analysis bioRxiv, doi: 10.1101/087866. | Link 15 Nov 2016 | Published in J Cell Sci 15 May 2017
> Wood, L.A., Clarke, N.I., Sarkar, S. & Royle, S.J. (2016) Hot-wiring clathrin-mediated endocytosis in human cells bioRxiv, doi: 10.1101/061986. | Link 4 Jul 2016 | Published in J Cell Biol 26 Sep 2017
> Gutiérrez-Caballero, C., Burgess, S.G., Bayliss, R. & Royle, S.J. (2014) TACC3–ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation bioRxiv, doi: 10.1101/008359. | Link 21 Aug 2014 | Published in Biol Open 16 Jan 2015
> Willox, A.K., Sahraoui, Y.M.E. & Royle, S.J. (2014) Non-specificity of Pitstop 2 in clathrin-mediated endocytosis bioRxiv, doi: 10.1101/002675. | Link 13 Feb 2014 | Published in Biol Open 4 Apr 2014
> Kaur, S., Fielding, A.B., Gassner, G., Carter, N. J. & Royle, S.J. (2014) An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis bioRxiv, doi: 10.1101/001701. | Link 09 Jan 2014 | Published in eLife 18 Feb 2014
* = equal contribution

Reviews

	> Sittewelle, M., Ferrandiz, N., Fesenko, M. & Royle, S.J. (2023) Genetically encoded imaging tools for investigating cell dynamics at a glance J. Cell Sci., 136 (7): jcs260783. | Link
	> Larocque, G. & Royle, S.J. (2022) Integrating intracellular nanovesicles into integrin trafficking pathways and beyond Cell. Mol. Life Sci., 79: 335. | Link
	> Shah, P., Chaumet, A., Royle, S.J. & Bard, F.A. (2019) The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors. Cells, 33: 119-20. | Link
	> Wood, L.A. & Royle, S.J. (2015) Zero Tolerance: Amphipathic Helices in Endocytosis. Dev. Cell, 33: 119-20. | Link
	> Royle, S.J. (2015) Super-duper resolution imaging of mitotic microtubules. Nat. Rev. Mol. Cell Biol., 16: 67. | Link
	> Royle, S.J. (2013) Protein adaptation: mitotic functions for membrane trafficking proteins. Nat. Rev. Mol. Cell Biol., 14: 592-9. | Link | PDF
	> Fielding, A.B. & Royle S.J. (2013) Mitotic inhibition of clathrin-mediated endocytosis. Cell Mol. Life Sci., 70: 3423-33. | Link | PDF
	> Royle, S.J. (2012) The role of clathrin in mitotic spindle organisation. J. Cell Sci., 125: 19-28. | Link | PDF
	> Hood, F.E. & Royle, S.J. (2011) Pulling it together: the role of TACC3 in mitosis. BioArchitecture, 1: 105-9. | Link | PDF
	> Royle, S.J. (2011) Mitotic moonlighting functions for membrane trafficking proteins. Traffic, 12: 791-8. | Link | PDF
	> Royle, S.J. & Lagnado, L. (2010) Clathrin-mediated endocytosis at the synaptic terminal: bridging the gap between physiology and molecules. Traffic, 11: 1489-97. | Link | PDF | On the cover
	> Granseth, B., Odermatt, B., Royle, S.J. & Lagnado, L. (2007) Clathrin-mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses. J. Physiol., 585: 681-6. | Link | PDF
	> Royle, S.J. (2006) The cellular functions of clathrin. Cell Mol. Life Sci., 63 (16): 1823-32. | Link | PDF
	> Royle, S.J. & Lagnado, L. (2003) Endocytosis at the synaptic terminal. J. Physiol., 553: 345-55. | Link | PDF
	> Royle, S.J. & Murrell-Lagnado, R.D. (2003) Constitutive cycling: a general mechanism to regulate cell surface proteins. Bioessays, 25: 39-46. | Link | PDF

Methods and Book Chapters

	> Ferrandiz, N. & Royle*, S.J. (2023) 3D Ultrastructural Visualization of Mitosis Fidelity in Human Cells Using Serial Block Face Scanning Electron Microscopy (SBF-SEM). Bio Protoc., 13:e4708. | Link
	> Wood, L.A. & Royle*, S.J. (2018) Imaging "Hot-Wired" Clathrin-Mediated Endocytosis. Methods Mol. Biol., 1847:83-94. | Link | PDF
	> Clarke, N.I. & Royle*, S.J. (2018) Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture. Methods Cell Biol., 145: 29-43. | Link | PDF
	> Booth*, D.G., Cheeseman*, L.P., Prior**, I.A. & Royle**, S.J. (2013) Studying kinetochore-fiber ultrastructure using correlative light-electron microscopy. Methods Cell Biol., 115: 327-42. | Link | PDF
	> Royle, S.J. Granseth, B., Odermatt, B., Derevier, A. & Lagnado, L. (2008) Imaging pHluorin-based probes at hippocampal synapses. Methods Mol. Biol., 457: 293-303. | Link | PDF

 

* = equal contribution
** = joint corresponding authors
For the latest publications and citations:

> Search for Steve's papers on Pubmed
> Steve's Google Scholar Profile
> ORCID
> ImpactStory
> Europe PMC
> Scopus profile

Other publications and outputs

Datasets

> Shelford, J. & Royle, S.J. (2020) Comparing antibodies for the detection of ch-TOG/CKAP5 in mitotic HeLa cells by indirect immunofluorescence. figshare. Figure. doi: https://doi.org/10.6084/m9.figshare.13395554.v1 | Link 17 Dec 2020

Software

> TrackMateR doi: https://doi.org/10.5281/zenodo.453722113
> CellMigration doi: https://doi.org/10.5281/zenodo.4850277
> CellShape doi: https://doi.org/10.5281/zenodo.3959278

Software under public development is usually at Steve's github repo. The lab GitHub and the CMCB GitHub have forks of our popular projects.

Other publications

> Avissar-Whiting, M., Belliard, F., Bertozzi, S. M., Brand, A., Brown, K., Clément-Stoneham, G., Dawson, S., Dey, G., Ecer, D., Edmunds, S. C., Farley, A., Fischer, T. D., Franko, M., Fraser, J. S., Funk, K., Ganier, C., Harrison, M., Hatch, A., Hazlett, H., Hindle, S., Hook, D.W., Hurst, P., Kamoun, S., Kiley, R., Lacy, M.M., LaFlamme, M., Lawrence, R., Lemberger, T., Leptin, M., Lumb, E., MacCallum, C.J., Marcum, C.S., Marinello, G., Mendonça, A., Monaco, S., Neves, K., Pattinson, D., Polka, J.K., Puebla, I., Rittman, M., Royle, S.J., Saderi, D., Sever, R., Shearer, K., Spiro, J.E., Stern, B., Taraborelli, D., Vale, R., Vasquez, C.G., Waltman, L., Watt, F.M., Weinberg, Z.Y. & Williams, M. (2024) Recommendations for accelerating open preprint peer review to improve the culture of science. PLoS Biology, 22(2), e3002502. | Link 01 Mar 2024

Journal covers