Current Lab Members

Click on a lab member to find out more | Alumni | Lab Map | Join Us | Lab Fun

I'm interested in things that cells do: how they move proteins around, how they divide and how they move. I did my undergrad at University of Sheffield and my PhD in the Department of Pharmacology at University of Cambridge. Next I did a post-doc with Leon Lagnado at the MRC Laboratory of Molecular Biology and started my own group in 2006/7 at Liverpool, moving the lab to Warwick in 2013.
Besides being PI, my role in the lab is doing programming and data analysis in collaboration with everyone in the group.

ORCiD: <a href=''>0000-0001-8927-6967</a>
GitHub: <a href=''>quantixed</a>
Twitter: <a href=''>@clathrin</a>
quantixed: <a href=''>Link</a>
Steve Royle
Principal Investigator

I am primarily a molecular and cellular biologist with a strong biochemistry and pharmacology background. Throughout my career I have expanded my knowledge in the area of genomic instability and chromosome biology in Mitosis and Meiosis field.
During my PhD in Professor Javier Leon Laboratory at the Institute of Biomedicine and Biotechnology (IBBTEC), I delivered a previously uncharacterised non-cell cycle role for a known tumour suppressor protein in mammalian cellular models. For my postdoctoral training in Dr Martinez-Perez laboratory at Imperial College, I have elucidated the mechanisms that promote correct chromosome segregation during oogenesis in multicellular organisms. Currently, I am working in Dr Steve Royle laboratory at Warwick University, in a project investigating how unaligned chromosomes in mitosis are ensheathed in membrane, phenomenon that potentially could change the way we think about mechanism underlying aneuploidy during tumour cell progression.

KEY WORDS: Mitosis, Meiosis, Chromosome segregation, Anueploidy, Spindle Assembly Checkpoint, Ensheathing chromosomes, Human Sterility and Tumour cells
ORCiD: <a href=''>0000-0002-7410-3470</a>
ResearcherID: <a href=''>V-4071-2017</a> Nuria Ferrándiz Díaz

I am a protein biochemist with a strong background in high-resolution spectroscopy and imaging techniques. During my PhD under the guidance of Prof. Mrinalini Puranik at the Indian Institute of Science Education and Research, Pune, India, I used vibrational spectroscopy to study enzyme-substrate interactions and protein dynamics.

I went on to do my postdoctoral training in the laboratory of Prof. Yale E. Goldman at the University of Pennsylvania, USA. My project at Penn involved determining stepping mechanism of molecular motors using single-molecule advanced imaging techniques and quantitative analysis.

My work in Prof. Steve Royle’s laboratory at the University of Warwick involves studying the binding modes of structural proteins that are involved in stabilizing spindle assembly during mitosis, using multiple biochemical and biophysical techniques..

ORCiD: <a href=''>0000-0001-7292-7823</a> Vishakha Karnawat

I am a trained cell biologist interested in mitosis and genome instability. I completed my PhD at the School of Cancer Sciences at the University of Birmingham where I characterised a protein previously unknown for its roles in the regulation of the cell cycle and genome instability.
I joined Steve’s lab as a postdoctoral researcher in September 2016. In my current role I am interested in characterising proteins that stabilise the mitotic spindle using a combination of CRISPR, light and electron microscopy.
I am also passionate about public engagement and like to involve myself in science communication whenever I can.

ORCiD: <a href=''>0000-0001-7426-2036</a>
Twitter: <a href=''>@ellislouiseryan</a> Ellis Ryan

I joined the team of Prof Steve Royle to study the role of TPD52-like proteins, markers of intracellular nanovesicles (INVs), in membrane trafficking and cell migration.
Prior to that, I completed my PhD in Pr Anne-Hélène Monsoro-Burq’s lab at Institut Curie in France during which I investigated a non-canonical role of a glycolytic enzyme on cell signalling and cell migration, in both context of human melanoma cells and amphibian neural crest development.
Before this, I did my undergraduate study in cell biology and development at the University of Paris-Saclay.

ORCiD: <a href=''>0000-0002-9383-6653</a> Méghane Sittewelle

I am a PhD student on the BBSRC-funded Midlands Integrative Biosciences Training Partnership (MIBTP) programme. I am interested in mitosis and I am looking at chromosome missegregation during cell division.
Previously, I have received BSc Molecular & Cellular Biology (with Biotechnology) from the University of Glasgow, completing an investigation into cellular response to surface topography in my final year. I then continued study at the University of Glasgow, completing a Master of Research degree, during which I investigated the possible interaction of a cell cycle regulator with a structural protein in fission yeast cytokinesis, and also the potential of specific stickleback populations as evolutionary mutant models of diabetes.

ORCiD: <a href=''>0000-0001-9039-942X</a> Laura Downie
PhD Student

I received my BSc in Molecular Biology and Genetics from Bilkent University, Ankara. During my second year, I worked as a summer research intern in UT Southwestern Medical Centre, Dallas, TX on Rabs in Drosophila brains and imaginal discs. After completing my MSc on modeling Charcot-Marie-Tooth disease in Drosophila at Bogazici University, Istanbul, I worked as a Product Manager at Gen Era Diagnostics, Istanbul, developing marketing strategies for life sciences and oncology products and organizing promotional events.
I’m now a PhD student on the Synthetic Biology CDT, a joint program between Warwick, Bristol and Oxford. I’m interested in membrane trafficking and am currently working on increasing the functionality of GFP in the cell.

ORCiD: <a href=''>0000-0002-7992-3523</a>
LinkedIn: <a href=''>cansukuey</a>
Twitter: <a href=''>@pixycus</a>
Google Scholar: <a href=''>Link</a> Cansu Küey
PhD Student

I’m a PhD student on the Medical Research Council Doctoral Training Partnership in Interdisciplinary Biomedical Research Programme.

I am interested intracellular membrane trafficking. My project involves proteins of the Tumor Protein D52 family and intracellular trafficking. My previous mini-project was developing quantitative methods to measure cortical actin during macropinocytosis.

Before Warwick I completed a BSc at the University of York in Biomedical Sciences, with my final year project characterising the role of the ubiquitous mammalian membrane protein cellugyrin. I also undertook two summer studentships with the Cambridge Institute of Medical Research and Cancer Research UK Cambridge studying cytotoxic T cell killing.

ORCiD: <a href=''>0000-0003-1553-0939</a> Daniel Moore
PhD Student

I am a PhD student on the ARAP programme at University of Warwick with a two-year attachment at the A-STAR research institute, Singapore, supervised by Steve Royle and co-supervised by Fred Bard. I work on membrane trafficking and my PhD project involves studying a novel endocytic pathway discovered by the Bard Lab, in which vesicles called Nuclear-Envelope Associated Endosomes (NAEs) translocate from the plasma membrane to the nuclear envelope. I will work on characterising these vesicles and the pathway they take to nucleus.
Prior to my PhD I studied the University of Essex for my Bachelor’s and at Imperial College London for my Master’s, working on the effects of Hepatitis C Virus infection and its effects on the cell cycle.

ORCiD: <a href=''>0000-0001-5679-9702</a>
LinkedIn: <a href=''>Link</a> Poonam Shah
PhD student

I am currently studying for a PhD on the <a href=''>MIBTP</a> programme, a BBSRC funded Doctoral Training Partnership between the University of Warwick, the University of Birmingham and the University of Leicester. I am interested in mitotic spindle stability and am currently investigating mechanisms for new microtubule nucleation in the mitotic spindle, supervised by Steve Royle and co-supervised by <a href=''>Richard Bayliss</a>. 
Prior to starting my PhD I studied Biochemistry at the University of Warwick pursuing a fourth year research project on the functionality of lignocellulosic degrading enzymes in fungi.

ORCiD: <a href=''>0000-0002-4546-9844</a>
LinkedIn: <a href=''>Link</a> James Shelford
PhD Student

I am a Research Fellow in Computing and Image Analysis working in CAMDU, the Computing and Advanced Microscopy Unit.
My role is to support image analysis in Biomedical Sciences at Warwick Medical School and maintain research computing infrastructure such as our OMERO database and our ELNs.

<a href=''>CAMDU</a> Laura Cooper
Honorary Member