Cross Lab

Rob

What we do

Work in my lab focuses on the force generating mechanisms of kinesins and microtubules.

We are trying to understand the molecular mechanisms of mechanochemical coupling. These mechanisms drive much of the self-organisation behaviour of eukaryotic cells and understanding them is important both for fundamental science and for the development of improved chemical biology approaches to a range of important medical and agricultural problems.

CV | Google scholar | Pubmed | UoW

WiA

 

Robert A. Cross (2016)
Mechanochemistry of the kinesin-1 ATPase

Biopolymers DOI: 10.1002/bip.22862
[Open]


Frauke Hussmann, Douglas R. Drummond, Daniel Peet, Douglas S. Martin & Robert A. Cross (2016)
Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism

Nature Scientific Reports DOI: 10.1038/srep20653
[Open]


 

All Papers | Lab Meeting Schedule | MariesGarage

In August 2016 our intern, Atreyi Chakrabarty, iphone-interviewed Cross lab members, starting by asking them what first drew them into science.

  1. Rob
  2. Naomi
  3. Algirdas
  4. Dan
  5. Nick
  6. Neil
  7. Atreyi
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Project content

Rob Cross | Mechanochemistry of kinesins and tubulins

My lab is trying to understand the mechanisms by which kinesins and microtubules generate force.


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Naomi Sheppard | Tubulin mechanochemistry

I am a Research Assistant working on the mutagenesis and protein chemistry of tubulins.



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Algirdas Toleikis | Kinesin backstepping

I want to find out how kinesin molecular motors walk backwards.


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Dan Peet | Kinesins and microtubule dynamics

Kinesin motors can influence microtubule dynamics. I am interested in understanding how this works.



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Nick Carter | Advanced Microscopy

I am interested in the single molecule mechanics of molecular motors and tracks. I am also designer and developer of the Warwick Open Source Microscope, an ultra stable open source platform for advanced optical microscopy.



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Neil Jenkins | Kinesin Crowds

I am analysing and simulating the stepping behaviour of processive kinesins, aiming to make predictions of the behaviour of teams of kinesins.



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Atreyi Chakrabarty | Intern

I am an undergraduate at Cambridge, strongly interested in Biophysics. I made these videos!



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>> Cross lab Alumni