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SteveCell biology at the molecular level

We are interested in two processes fundamental to eukaryotic cellular life: mitosis and membrane trafficking. We want to understand how these processes operate at the molecular level in the hope of identifying new strategies to prevent tumour formation and propagation in cancer and to inhibit cellular infection.

Click on the links to find out more about our work and about the people in the lab.

labThis is us!

You can meet all the people in the lab by heading to the people section.

>> [People]

clathrinPut your coat on

Collaboration with Corinne Smith's lab explains how adaptors drive clathrin coat assembly.

>> Smith et al. (2021) | [Paper] | [Plain English]

migrationI like to move it, move it

Gabrielle and others found that integrin traffic during cell migration happens via small transport vesicles.

>> Larocque et al. (2021) | [Paper] | [Plain English]

crisprFollow the leader

Ellis and James show how endogenous knocksideways can be used to define a protein complex.

>> Ryan and Shelford et al. (2020) | [Paper]

LarocqueHello, World!

Gabrielle discovered a novel class of transport vesicle in cells.
We call them INVs - intracellular nanovesicles. We found them by examining a protein called TPD54, one of the most abundant proteins in human cells.

>> Larocque et al. (2019) | [Paper] | [Plain English]



See all of our papers here