We are interested in two processes fundamental to eukaryotic cellular life: mitosis and membrane trafficking. We want to understand how these processes operate at the molecular level in the hope of identifying new strategies to prevent tumour formation and propagation in cancer and to inhibit cellular infection.
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Ellis and James show how endogenous knocksideways can be used to define a protein complex.
>> Ryan and Shelford et al. (2020) | [Paper]
Gabrielle discovered a novel class of transport vesicle in cells.
We call them INVs - intracellular nanovesicles. We found them by examining a protein called TPD54, one of the most abundant proteins in human cells.
>> Larocque et al. (2019) | [Paper] | [Plain English]
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