06 February 2017
Organised by:
Rob Cross (Centre for Mechanochemical Cell Biology, Warwick Medical School)
Mathias Gautel (Randall Institute, Kings College London)
Work at our two institutions aims to understand the contributions of mechanical and mechanochemical mechanisms to cell function. To learn about each other's work and to facilitate progress, we have organised this one day joint Symposium in Molecular and Cellular Mechanobiology, with support from the Wellcome Trust. We will discuss topics ranging from single molecule dynamics of molecular motors to the mechanics of muscle contraction and cell crawling.
PROGRAMME - Monday 06 February 2017 |
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09:00 – |
Doors open
to Randall contingent |
|
10:00 – |
Scheduled
arrival of Warwick contingent |
|
10:20 – 10:40 | M.Balasubramanian
|
Cytokinesis
in vitro and in vivo
|
10:40 –
11:00 |
M. Mishima |
Mechanical robustness and plasticity of cytokinesis |
11:00 –
11:30 |
Tea/Coffee | |
11:30 –
11:50 |
M. Irving |
Mechano-sensing in muscle: maximising the ratio of performance to metabolic cost |
11:50 –
12:10 |
M. Gautel |
Mechanobiology of titin - the challenges |
12:10 –
12:30 |
S. Hughes |
Fishing for the role of force in muscle growth |
12:30 – 12:50 | A. Straube |
Self-organisation of microtubule arrays in skeletal muscle cells |
13:00 – |
Lunch | |
14:00 – 14:20 | S. Royle | Re-engineering cells to study endocytosis |
14:20 –
14:40 |
V.
Sanz-Moreno |
Cell Migration and Beyond: Actomyosin Contractility as a key regulator of tumour biology |
14:40 – 15:00 | B. Stramer |
Cytoskeletal mechanics of cell migration and embryonic morphogenesis |
15:00 – 15:20 | R. Cross |
Structural-mechanical remodelling of GDP-microtubules by kinesin |
15:30 – |
Tea/coffee | |
16:00 – 16:20 | S.
Garcia-Manyes |
Linking
mechanochemistry with protein folding with single bond
resolution |
16:20 –
16:40 |
A. McAinsh |
Mechanical performance of the kinetochore |
16:40 – 17:00 | C.
Chiappini |
Engineering high-aspect ratio nanomaterials to direct cell fate |
17:15 –
19:00 |
Evening
Reception (Gordon Museum of Physiology) |