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Harry EF, McAinsh AD, Burroughs NJ. (2015)
Inferring the Forces Controlling Metaphase
Kinetochore Oscillations by Reverse Engineering
System Dynamics.
PLoS Computational Biology Nov 30;11(11):e1004607.
[Open
access]
**Burroughs,
N.J., Harry, E.F. and **McAinsh, A.D. (2015)
Super-resolution kinetochore tracking reveals the
mechanisms of human sister kinetochore directional
switching
eLife 2015;10.7554/eLife.09500
[link]
Straube, A.
(2015)
Microtubules and Microtubule-Associated Proteins
(MAPs).
Encyclopedia of Cell Biology, Volume 2: Organizational
Cell Biology, 2016, Pages 539-547
[link]
[request
pdf]
Auckland, P.
and McAinsh, A.D. (2015)
Building an integrated model of chromosome
congression.
Journal of Cell Science, 128: 3363-74
[link]
Nixon, F.M.,
Gutiérrez-Caballero, C., Hood, F.E., Booth, D.G.,
Prior, I.A. & Royle, S.J. (2015)
The mesh is a network of microtubule connectors that
stabilizes individual kinetochore fibers of the
mitotic spindle.
eLife, 4: e07635. doi: 10.7554/eLife.07635
[link]
[press]
[blog]
Lee, K.Y.,
Esmaeili, B., Zealley, B. & Mishima, M. (2015)
Direct interaction between centralspindlin and PRC1
reinforces mechanical resilience of the central
spindle.
Nature Communications, 6: 7290. doi:
10.1038/ncomms8290
[link]
Quach, H.N.,
Tao, S., Vrljicak, P., Joshi, A., Ruan, H., Sukumaran,
R., Varshney, G.K., LaFave, M.C., Ds Screen Team,
Burgess, S.M., Winkler, C., Emelyanov, A., Parinov,
S., & Sampath, K. (2014)
A Multifunctional Mutagenesis System for Analysis of
Gene Function in Zebrafish.
G3 (Bethesda), 5: 1283-99.
[link]
Lobo, D.P.
,Wemyss, A.M., Smith, D.J., Straube, A., Betteridge,
K.B., Salmon, A.H.J., Foster, R.R., Elhegni, H.E.,
Satchell, S.C., Little, H.A., Pacheco-Gomez, R.,
Simmons, M.J., Hicks, M.R., Bates, D.O., Rodger, A.,
Dafforn, T.R., & Arkill, K.P. (2015)
Direct detection and measurement of wall shear
stress using a filamentous bio-nanoparticle.
Nano Research, doi: 10.1007/s12274-015-0831-x [link]
Nahorski,
M.S., Al-Gazali, L., Hertecant, J., Owen, D.J.,
Borner, G.H.H., Chen, Y., Benn, C.L., Carvalho, O.P.,
Shaikh, S.S., Phelan, A., Robinson, M.S., Royle, S.J.
& Woods, C.G. (2015)
A novel disorder reveals clathrin heavy chain-22 is
essential for human pain and touch development.
Brain, doi: 10.1093/brain/awv149
[link]
O'Regan, L.,
Sampson, J., Richards, M.W., Knebel, A., Roth, D.,
Hood, F.E., Straube, A., Royle, S.J., Bayliss, R.
& Fry, A.M. (2015)
Hsp72 is targeted to the mitotic spindle by Nek6 to
promote K-fiber assembly and mitotic progression.
The Journal of Cell Biology, 209: 349-358.
doi:10.1083/jcb.201409151
[link]
Davies, T.,
Kodera, N., Kaminski Schierle, G.S., Rees, E.,
Erdelyi, M., Kaminski, C.F., Ando, T. & Mishima,
M. (2015)
CYK4 Promotes Antiparallel Microtubule Bundling by
Optimizing MKLP1 Neck Conformation.
PLoS Biology, 13: e1002121. doi:
10.1371/journal.pbio.1002121
[link]
Meadows,
J.C. & Millar, J.B. (2015)
Sharpening the anaphase switch.
Biochemical Society Transactions, 43: 19-22.
[link]
Armond J.W.*,
Vladimirou E.*, Erent M., McAinsh A.D.** &
Burroughs N.J.** (2015)
Probing microtubule polymerisation state at single
kinetochores during metaphase chromosome motion.
Journal of Cell Science, 128: 1991-2001. doi:
10.1242/jcs.168682
[Open Access PDF]
Mogessie, B.,
Roth, D., Rahil, Z. and Straube, A. (2015)
A novel isoform of MAP4 organises the paraxial
microtubule array required for muscle cell
differentiation
eLife, 4: e05697. doi:10.7554/eLife.05697.
[link] | [PDF]
Wood, L.A. &
Royle, S.J. (2015)
Zero Tolerance: Amphipathic Helices in Endocytosis
Developmental Cell, 33: 119-20.
[link]
Richards, M.W.,
O'Regan, L., Roth, D., Montgomery, J.M., Straube, A.,
Fry, A.M. and Bayliss, R. (2015)
Microtubule association of EML proteins and the
EML4-ALK variant 3 oncoprotein require an N-terminal
trimerization domain
Biochemical Journal, 467: 529-536.
doi:10.1042/BJ20150039
[link]
Gutiérrez-Caballero, C., Burgess, S.G., Bayliss, R.
& Royle, S.J. (2015)
TACC3–ch-TOG track the growing tips of microtubules
independently of clathrin and Aurora-A
phosphorylation
Biology Open, 4: 170-9.
[OA]
[preprint]
Bachmann,
A. and Straube, A. (2015)
Kinesins in cell migration
Biochem Soc Trans, 43(1): 79-83.
[PDF] |
[pubmed]
Royle, S.J. (2015)
Super-duper resolution imaging of mitotic
microtubules
Nature Reviews Molecular Cell Biology, 16: 67.
[link]
*Bancroft, J.,
*Auckland, P., Samora, C.P. and McAinsh A.D. (2015)
Chromosome congression is promoted by CENP-Q- and
CENP-E-dependent pathways
Journal of Cell Science, 128, 171-184.
doi:10.1242/jcs.163659
[Open Access PDF]
*equal contribution; **joint corresponding authors
Srinivasan,
R. & Balasubramanian, M.K.(2014)
Bacteria spring a surprise.
eLife, 3: e03435.
[link]
Tao, E.Y.,
Calvert, M. & Balasubramanian, M.K.(2014)
Rewiring Mid1p-independent medial division in
fission yeast
Current Biology, 24: 2181-8.
[link]
McAinsh A.D.
(2014)
How Kinetochores CCAN resist force
Developmental cell 30 (6), 637-638
[link]
Efimova,
N., Grimaldi, A., Bachmann, A., Frye, K., Zhu, X.,
Feoktistov, A., Straube, A. and Kaverina, I. (2014)
Podosome-regulating kinesin KIF1C translocates to
the cell periphery in a CLASP-dependent manner.
Journal of Cell Science 127: 5179-5188.
doi:10.1242/jcs.149633
[link]
Messin, L.J.
& Millar, J.B. (2014)
Role and regulation of kinesin-8 motors through the
cell cycle.
Systems and Synthetic Biology, 8: 205-13.
[link]
Grimaldi, A.D.,
Maki, T., Fitton, B.P., Roth, D., Yampolsky, D.,
Davidson, M.W., Svitkina, T., Straube, A., Hayashi, I.
and Kaverina, I. (2014)
CLASPs are required for proper microtubule
localization of end-binding proteins.
Developmental Cell, 30, 343-352.
[link]
López-Murcia,
F.J., Royle, S.J. & Llobet, A. (2014)
Presynaptic clathrin levels are a limiting factor
for synaptic transmission
J Neurosci 34: 8618-8629.
[link]
Willox, A.K.,
Sahraoui, Y.M.E. & Royle, S.J. (2014)
Non-specificity of Pitstop 2 in clathrin-mediated
endocytosis.
Biology Open 3: 326-31. doi: 10.1242/bio.20147955
bioRxiv doi:10.1101/002675
[link]
[preprint]
Cross
RA and McAinsh AD (2014)
Prime movers: the mechanochemistry of mitotic
kinesins.
Nature Reviews Molecular Cell Biology 15:257-271
[link]
Drechsler, H.,
McHugh, T., Singleton, M.R., Carter, N.J. and McAinsh,
A.D. (2014)
The kinesin-12 Kif15 is a processive track-switching
tetramer
eLife 3: e01724; PMID: 24668168
[pdf]
[press release]
[lens]
[lay summary]
Vazquez-Novelle M.
D., Sansregret, L., Dick, A., Smith, C. A., McAinsh,
A. D., Gerlich, D. W. and Petronczki, M. (2014)
Cdk1 Inactivation Terminates Mitotic Checkpoint
Surveillance and Stabilizes Kinetochore Attachments
in Anaphase
Current Biology 24: 1-8
doi.org/10.1016/j.cub.2014.01.034
[link]
Kaur, S.,
Fielding, A.B., Gassner, G., Carter, N. J. &
Royle, S.J. (2014)
An unmet actin requirement explains the mitotic
inhibition of clathrin-mediated endocytosis
eLife 3: e00829 doi: 10.7554/eLife.00829
[pdf]
[html]
[lens]
Katsuki, M.,
Drummond, D.R. & Cross, R.A. (2014)
Ectopic A-lattice seams destabilise microtubules
Nature Communications, 5: 3094 doi: 10.1038/ncomms4094
[open]
Marta Klejnot, Aditi
Falnikar, Venka Ulaganathan, Robert A. Cross, Peter W.
Baas, Frank Kozielski (2014)
The crystal structure and biochemical characterisation
of Kif15 - a bifunctional molecular motor involved in
bipolar spindle formation and neuronal development
Acta Crystallogr D Biol Crystallogr. 70(Pt 1):123-33
[link]
Wolman, A.J.M.,
Sanchez-Cano, C., Carstairs, H.M.J., Cross, R.A. &
Turberfield, A.J. (2014)
Transport and self-organization across different
length scales powered by motor proteins and
programmed by DNA
Nature Nanotechnology, 9:44-47 doi:
10.1038/nnano.2013.230
[link]
*equal contribution †corresponding authors
Vladimirou, E.*,
Mchedlishvili, N.*, Gasic, I.*, Armond, J.W., Samora,
C.P., Meraldi, P**. and McAinsh, A.D.** (2013)
Nonautonomous movement of chromosomes in mitosis.
Developmental Cell, 27: 60-71
[link]
Jefferyes, S.D.R.,
Epstein, D.B.A., Straube, A., Rajpoot, N.M. (2013)
A novel framework for exploratory analysis of highly
variable morphology of migrating epithelial cells.
Conf Proc IEEE Eng Med Biol Soc. 2013
Jul;2013:3463-3466, doi:10.1109/EMBC.2013.6610287
[link]
[pubmed abstract]
Royle,
S.J. (2013)
Protein adaptation: mitotic functions for membrane
trafficking proteins.
Nature Rev. Mol. Cell Biol. 14: 592-9.
doi:10.1038/nrm3641
[link]
Hood, F.E.,
Williams, S.J., Burgess, S.G., Richards, M.W., Roth,
D., Straube, A., Pfuhl, M., Bayliss, R. & Royle,
S.J. (2013)
Coordination of adjacent domains mediates
TACC3–ch-TOG–clathrin assembly and mitotic spindle
binding.
J. Cell Biol. 202:463-78
[link]
Earnshaw WC,
Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W,
Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai
A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D,
Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky
GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen
G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K,
Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh
AD, Mellone BG, Meraldi P, Musacchio A, Oegema K,
O'Neill RJ, Salmon ED, Scott KC, Straight AF,
Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE,
Swedlow JR, Walczak CE, Warburton PE, Westermann S,
Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K,
Cleveland DW. (2013)
Esperanto for histones: CENP-A, not CenH3, is the
centromeric histone H3 variant.
Chromosome Research 21:101-106
[pubmed abstract]
Mora-Santos,
M. & Millar, J.B. (2013)
Checkpoint proteins come under scrutiny.
eLife, 2: e01494.
[link]
Cheeseman, L.P.,
Harry, E.F., McAinsh, A.D., Prior, I.A. & Royle,
S.J. (2013)
Specific removal of TACC3-ch-TOG-clathrin at
metaphase deregulates kinetochore fiber tension.
J. Cell Sci., 126: 2102-13
[link
to pdf]
[pubmed abstract]
*equal contribution †corresponding authors
Theisen U, Straube
E, and Straube A. (2012)
Directional Persistence of Migrating Cells Requires
Kif1C-Mediated Stabilization of Trailing Adhesions.
Developmental Cell 23:1153-1166
[link
to pdf]
[pubmed abstract][request
pdf]
Eskat
A, Deng W, Hofmeister A, Rudolphi S, Emmerth S,
Hellwig D, Ulbricht T, Doring V, Bancroft JM, McAinsh
AD, Cardoso MC, Meraldi P, Hoischen C, Leonhardt H,
Diekmann S. (2012)
Step-Wise Assembly, Maturation and Dynamic Behavior
of the Human CENP-P/O/R/Q/U Kinetochore Sub-Complex.
PLOS ONE. 7:e44717
[link to pdf]
[pubmed abstract][request
pdf]
Erent, M.,
Drummond, D.R., Cross R.A (2012)
S. pombe kinesins-8 promote both nucleation and
catastrophe of microtubules
PLoS ONE 7, e30738 - e30738
[link
to pdf]
Kaseda, K.,
McAinsh, A.D. & Cross, R.A. (2012)
Dual pathway spindle assembly increases both the
speed and the fidelity of mitosis
Biology Open, Nov 2. doi: 10.1242/bio.2011012
[link
to pdf] [Biology
Open website]
McAinsh,
A.D. & Straube, A. (2011)
Spindle Centricity
Cell Cycle, Advance Online Publication December 1
[link
to pdf][request
pdf]
Hellwig,
D., Emmerth, S., Ulbricht, t., Doring, V., Hoischen,
C., Martin, R., Samora. C, McAinsh, A.D., Carroll,
C.W., Straight, A.F., Meraldi, P., and Diekmann, S.
(2011)
Dynamics of CENP‐N kinetochore binding during the
cell cycle
J Cell Sci , Advance Online Publication November 18
[link
to pdf]
[pubmed abstract]
Grant,
B.J., Gheorghe, D., Zheng,W., Alonso, M., Huber, G.,
Dlugosz,M., McCammon, J.A. & Cross, R.A. (2011)
Electrostatically biased binding of kinesin to
microtubules
PLOS Biology 9(11) e1001207. Epub 2011 Nov 29
[link
to pdf]
[pubmed abstract]
McAinsh, A.D. & Meraldi, P.. (2011)
The CCAN complex: Linking centromere specification
to control of kinetochore-microtubule dynamics
Seminars in Cell and Developmental Biology, Oct 19.
[Epub ahead of print]
[link
to pdf]
[pubmed abstract]
Cross,
R.A., McAinsh, A.D. & Straube A. (2011)
Mechanochemical Cell Biology
Seminars in Cell and Developmental Biology, Oct 7.
[Epub ahead of print]
[link
to pdf]
[pubmed abstract]
Drummond,
D.R. (2011)
Regulation of microtubule dynamics by kinesins
Seminars in Cell and Developmental Biology, Oct 5.
[Epub ahead of print]
[link
to pdf]
[pubmed abstract]
Samora,
C.P.*, Mogessie, B.*, Conway, L., Ross, J.L., Straube,
A.** & McAinsh A.D.** (2011)
MAP4 and CLASP1 operate as a safety mechanism to
maintain a stable spindle position in mitosis.
Nature Cell Biology, 131040-1050
[link
to pdf]
[pubmed abstract]
Samora,
C.P & McAinsh A.D. (2011)
Photoactivatable-GFP-α-Tubulin as a Tool to Study
Microtubule Plus-End Turnover in Living Human Cells.
Methods in Molecular Biology, 777 223-33
[link
to pdf]
[pubmed abstract]
Drummond
D.R., Kain S., Newcombe A., Hoey C., Katsuki M., Cross
R.A. (2011)
Purification of Tubulin from the Fission Yeast
Schizosaccharomyces pombe.
Methods in Molecular Biology, 777 29-55
[link
to pdf]
[pubmed abstract]
Katsuki
M., Muto E., Cross R.A. (2011)
Preparation of dual-color polarity-marked
fluorescent microtubule seeds.
Methods in Molecular Biology, 777 117-26
[link
to pdf]
[pubmed abstract]
Vladimirou
E., Harry, E., Burroughs N. & McAinsh A.D. (2011)
Springs, clutches and motors: driving forward
kinetochore mechanism by modelling
Chromosome Biology, 19 409-21
[link
to pdf] [pubmed
abstract]
*equal contribution **corresponding authors
Amaro
AC, Samora CP, Holtackers R, Wang E, Kingston I,
Alonso M, Lampson L, McAinsh AD** and Meraldi P**
(2010)
Molecular control of kinetochore-microtubule
dynamics and chromosome oscillation
Nature Cell Biology, 12 319-329
[link
to pdf] [pubmed
abstract]
Jaqaman K*, King E*,
Amaro AC*, Winter JR*, Dorn JF, Elliott, HL,
Mchedlishvili N, McClelland SE, Porter IM, Posch M,
Toso A, Danuser G**, McAinsh AD**, Meraldi P**,
Swedlow JR** (2010)
Kinetochore alignment within the metaphase plate is
regulated by centromere stiffness and microtubule
depolymerases
Journal of Cell Biology, 188 665-79
[link
to pdf] [pubmed
abstract]
*equal contribution **corresponding authors
Hawkins T.L., Sept
D., Mogessie B., Straube A. and Ross J.L. (2013)
Drechsler
& McAinsh AD (2012)
Joseph,
N., Hutterer, A., Poser, I., Mishima, M. (2012)
Kaverina,
I. & Straube A. (2011)
Straube A. (2011)
Cross
RA (2010)