Work in the lab focuses on the force generating mechanisms of kinesins and microtubules.
O. Von Loeffelholz, A. Peña, D. R. Drummond, R. Cross, C. A. Moores (2019)
4.5 Å Cryo-EM Structure of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance [Link]
McHugh, T., Drechsler, H., McAinsh, A.D., Carter, N.J. & Cross R.A. (2018)
Kif15 functions as an active mechanical ratchet.
Mol Biol Cell. mbcE18030151. doi: 10.1091/mbc.E18-03-0151. [Link]
TOG domain MT polymerases accelerate MT plus end growth via electrostatically-steered diffusion-to-capture and electrostatic templating of GTP-tubulin | Venables et al (2018) | bioRxiv
Daniel R. Peet, Nigel J Burroughs, Robert A. Cross (2018)
Kinesin expands and stabilises the GDP-microtubule lattice | Nature Nano
I lead the Motors Group and am also Director of the CMCB and Director of the Hooke Science Programme, our radical new undergraduate course in Integrated Science.
I am interested in the single molecule mechanics of molecular motors and tracks & am designer and developer of the WOSM.
I am a scientific visitor to the Cross lab, working with Nick Carter and Claire Mitchell to develop the WOSM.
I am a PhD student, working on tubulin engineering and microtubule lattice mechanics.
I am a biophysicist, interested in how kinesins step.