mechanochemistry mechanochemistry mechanochemistry mechanochemistry mechanochemistry




autapseGetting depressed

Work from Steve Royle and the Llobet lab in Barcelona shows that clathrin levels set presynaptic function and that their run-down contributes to synaptic depression.
>> Journal of Neuroscience (2014) | link

pistopCaution: Pitstop

Testing the extent of non-specificity of the clathrin inhibitor Pitstop in clathrin-mediated endocytosis by the Royle lab.

>> Biology Open (2014) | link

kif15track switcher

McAinsh lab reveals the biochemical properties of the KIF15 motor protein thus providing key clues as to how it organises microtubule networks such as the mitotic spindle.
>> eLife (2014) | e-print | plain english | press release

endocytosisSwitch it off

When cells enter mitosis, they shut down endocytosis. A new paper from the Royle Lab describes how this process works.
>> eLife (2014) | e-print


The Cross lab finds that A-lattice seams are the Achilles' heels of microtubules.

>> Nature Communications (2014) | e-print

shuttle scuttleShuttle program

The Cross and Turberfield labs use DNA to program a kinesin-microtubule railway.

>> Nature Nanotechnology (2014) | link

kinetochoreLosing self-control

The McAinsh and Meraldi labs show that chromosome movement is non autonomous - and influenced by non-kinetochore motors KIF11 and KIF15.
>> Developmental Cell (2013) | link

clathrinSome assembly required

The Royle lab with Anne Straube and Richard Bayliss show how TACC3 and clathrin bind microtubules.

>> Journal of Cell Biology (2013) | link