Jess Patel reveals how kinetochores operate differently during meiosis in humans and how this may explain chromosome errors as maternal age increases.
>> Biology Open (2015) | open access
Burroughs and McAinsh use mathematical modelling to infer the forces controlling kinetochore motion.
>> PLOS Computational Biology (2015) | open access
Burroughs and McAinsh reveal how a force-sensitive molecular clock controls direction of kinetochore movements - a key requirement for chromosome positioning.
>> eLife (2015) | link
The Mishima lab shows that cells link PRC1 to centralspindlin to create a motorised crosslinker that actively maintains the integrity of the central spindle.
>> Nature Communications (2015) | link
McAinsh and Burroughs groups develop image analysis tools and live imaging to reveal how microtubule polymerisation is coordinated at sister kinetochores
>> Journal of Cell Science (2015) | Open Access PDF