Work in the lab focuses on the force generating mechanisms of kinesins and microtubules.
McHugh, T., Drechsler, H., McAinsh, A.D., Carter, N.J. & Cross R.A. (2018)
Kif15 functions as an active mechanical ratchet.
Mol Biol Cell. mbcE18030151. doi: 10.1091/mbc.E18-03-0151. [Link]
TOG domain MT polymerases accelerate MT plus end growth via electrostatically-steered diffusion-to-capture and electrostatic templating of GTP-tubulin | Venables et al (2018) | bioRxiv
Daniel R. Peet, Nigel J Burroughs, Robert A. Cross (2018)
Kinesin expands and stabilises the GDP-microtubule lattice | Nature Nano
I am a Research Assistant working on the mutagenesis and protein chemistry of tubulins.
I am interested in the single molecule mechanics of molecular motors and tracks & am designer and developer of the WOSM.
I am a PhD student, joint with the McAinsh lab, developing methods for magnetic nanomanipulation.